Over 100 years of Cyclodextrins.

1891 

Cyclodextrins, first discovered in 1891, have undergone extensive clinical testing and research over the years. These unique cyclic oligosaccharides have garnered significant scientific interest due to their diverse applications and potential benefits across various fields.

"α- and β CD's were discovered in 1891 by the French pharmacist and chemist Antoine Villiers as digestion products of potato starch obtained by using the bacteriumBacillus amylobacter."

Hal Science - 130 years of cyclodextrin discovery for health.

2000

"In 2000-2004, α-CD, β-CD and γ-CD were introduced into the generally regarded as safe (GRAS) list of the FDA for use as a food additive. Alpha- and beta-CD are approved as novel food ingredients by the Commission. Beta-CD is approved in Europe as a food additive"

Cyclodextrins Listed GRAS with FDA and EFSA

2009

"This study was carried out to determine optimum conditions for cholesterol removal from pasteurized nonhomogenized milk by adding β-cyclodextrin. The β-cyclodextrin (0.4, 0.6, 0.8, and 1.0%) removed from 65.42% to 95.31% of cholesterol at 4°C in 20min."

Science Direct - Use of β-cyclodextrin to decrease the level of cholesterol in milk fat.

2015

"Cyclodextrin has been shown in mice to dissolve cholesterol crystals and prevent plaque formation. The drug is already approved for use in humans and could be tested in patients to treat atherosclerosis."

Science Daily - Cyclodextrin dissolves away cholesterol crystals

2016

"CD treatment of murine atherosclerosis reduced atherosclerotic plaque size and CC load, and promoted plaque regression even with a continued cholesterol-rich diet."

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming

2021

"Australian produces CAVADEX (Beta-Cyclodextrin) which reverses heart disease by removing cholesterol from damaged and narrowed arteries after only a few months, resulting in reduced arterial plaque."

Yahoo - Molecule flushes away cholesterol and reverses blocked arteries

Please note the articles, quotes, and statements displayed on this page are authored by sources external to AtheroCare. These materials are intended solely for educational and research purposes.

 

 

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